Nah, despite what Intel would like you to believe, there really isn’t all that much to be gained between generations at this point. Sure, an 11th or 12th gen i7 will be faster, but we’re talking likely a 10-20% delta, if that.
Memory controller, UEFI Firmware… A number of reasons. You can always try, but you’re on your own / at your own risk.
For instance, I’ve got an ancient eMachines 633ids with an Intel Celeron 1.13GHz which had a max memory support of 64MB according to the OEM. That baby is running 2GB right now
I’m super tempted to try and over-RAM my ultra-small form-factor desktop (max supported on motherboard is 32GB, supposedly, 64GB by CPU/memory controller supposedly) to 128GB, but I’m not in a place where I can drop almost $1k on a FAAFO situation.