You could also create a geo.txt file according to the documentation if you don’t wish to directly modify the images themselves: https://docs.opendronemap.org/geo/
If you don’t have any georefence data, your products will obviously not be georeferneced at all, and may have translation, scale, skew, and other artifacting that will require you to correct them manually if they’re going to be used in a georeferenced project.